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RecombiMAb human IgG4 (S228P) isotype control antibody reactive with hen egg lysozyme, produced recombinantly in CHO cells and supplied as a purified antibody for use as an isotype control in antibody-based assays. The S228P mutation prevents IgG4 Fab arm exchange; formulation is PBS pH 7.0, purity ≥95%, supplied as a 25 mg vial; store at 4°C and do not freeze.
Recombinant human IgG4 with S228P mutation.
Reacts with hen egg lysozyme; minimal cross-reactivity to human samples.
Produced in CHO cells in an animal-free facility.
Purity ≥95% as determined by SDS-PAGE.
Formulated in PBS, pH 7.0, no stabilizers or preservatives.
Supplied as a 25 mg vial; store at 4°C, do not freeze.
Intended for use as an isotype control in antibody assays.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
An inhibitor of the Rho GEF 12-RhoA protein-protein interaction binds to the DH-PH domain of Rho GEF 12 in a cell-free assay (Kd 76 nM) inhibits serum-induced phosphorylation of MLC and FAK a marker of RhoA activity in NIH3T3 cells at 10 and 30 UM inhibits cell growth migration invasion and mammosphere formation in MCF-7 breast cancer cells from 5-30 UM
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Active Motif's Protein G Agarose Beads are the same beads that are included in our Protein G Agarose Columns, which are sold separately or in our ChIP-IT High Sensitivity Kit. The beads have been specifically engineered to greatly reduce non-specific binding. They have a binding capacity of 10 ug IgG/ul bead and are provided as a 50% slurry. The beads should be washed with TE, pH 8.0 prior to use in chromatin immunoprecipitation reactions.
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Protein G Mag Sepharose(R) are magnetic beads designed to simplify enrichment of target proteins by immunoprecipitation applications. Based on Sepharose(R) with Protein G as ligand. Protein G has high affinity for the fc region of IgG antibodies.
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